MovDisordV3, Main, Exploration, bibRecord, 003669

123I-ioflupane SPECT in the diagnosis of suspected psychogenic parkinsonism

Identifieur interne : 003669 ( Main/Exploration ); précédent : 003668; suivant : 003670

123I-ioflupane SPECT in the diagnosis of suspected psychogenic parkinsonism

Auteurs : Caries Gaig [Espagne] ; Maria José Martf [Espagne] ; Eduardo Tolosa [Espagne] ; Francesc Valldeoriola [Espagne] ; Pilar Paredes [Espagne] ; Francisco Juan Lomena [Espagne] ; Fernando Nakamae [Espagne]

Source :

Movement disorders [ 0885-3185 ] ; 2006.

RBID : Pascal:07-0021734

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Parkinsonisme, Tomoscintigraphie émission monophotonique, Photon, Diagnostic, Psychogène, Parkine, Mutation.

English descriptors

KwdEn :
- Diagnosis, Mutation, Nervous system diseases, Parkin, Parkinsonism, Photon, Psychogenic, Single photon emission tomography.

Abstract

Psychogenic Parkinsonism (PsyP) can be clinically difficult to differentiate from Parkinson's disease (PD). Striatal dopamine transporter (DAT) imaging could be helpful in differentiating them. We performed ¹²³I-Ioflupane single-photon emission computed tomography (SPECT) in 9 patients with suspected PsyP. In 1 patient, ¹²³I-Ioflupane SPECT disclosed bilateral decrease of striatal tracer uptake that indicated nigrostriatal degeneration. In this patient, a parkin gene mutation was detected. In the other 8 patients, ¹²³I-Ioflupane SPECT was normal and supported the initial suspicion of PsyP. Normal DAT imaging supports the diagnosis of PsyP, whereas reduced striatal tracer uptake suggests an underlying neurodegenerative Parkinsonism and should encourage the search for additional causes for the syndrome.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 001897
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to stream PascalFrancis, to step Checkpoint: 001C55
to stream Main, to step Merge: 004D50
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Le document en format XML

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I-ioflupane SPECT in the diagnosis of suspected psychogenic parkinsonism</title>
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I-ioflupane SPECT in the diagnosis of suspected psychogenic parkinsonism</title>
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<front><div type="abstract" xml:lang="en">Psychogenic Parkinsonism (PsyP) can be clinically difficult to differentiate from Parkinson's disease (PD). Striatal dopamine transporter (DAT) imaging could be helpful in differentiating them. We performed <sup>123</sup>
I-Ioflupane single-photon emission computed tomography (SPECT) in 9 patients with suspected PsyP. In 1 patient, <sup>123</sup>
I-Ioflupane SPECT disclosed bilateral decrease of striatal tracer uptake that indicated nigrostriatal degeneration. In this patient, a parkin gene mutation was detected. In the other 8 patients, <sup>123</sup>
I-Ioflupane SPECT was normal and supported the initial suspicion of PsyP. Normal DAT imaging supports the diagnosis of PsyP, whereas reduced striatal tracer uptake suggests an underlying neurodegenerative Parkinsonism and should encourage the search for additional causes for the syndrome.</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

123I-ioflupane SPECT in the diagnosis of suspected psychogenic parkinsonism

123I-ioflupane SPECT in the diagnosis of suspected psychogenic parkinsonism

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri